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Remodelling of the infarcted heart: piezoelectric multifunctional patch enabling the sequential release of therapeutic factors

Project

The project’s ambition is to provide a multifunctional and intelligent cardiac patch with the aim of preventing heart failure in patients who survive an acute myocardial infarction

Objectives

Development of an acellular piezoelectric patch that allows the release of proliferative, anti-inflammatory, anti-fibrotic, reducing arrhythmogenic risks

Impacts

REBORN has potential find one advanced solution that will provide a paradigm shift in capability for the treatment of patients who have suffered a myocardial infarction.

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PARTNERS
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COUNTRIES INVOLVED
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EU CONTRIBUTION

Focus

REBORN will respond to this unmet clinical need by means of a synergistic integration of multifunctional biomaterials and electrospinning technology (ESP) to deliver a fibrous piezoelectric patch able to provide the full set of cues required to promote a functional heart tissue remodelling.

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Our Partners involved

The consortium involves 12 partners distributed over 6 European countries: Italy, Portugal, United Kingdom, Spain, Germany and Belgium

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Chiara Vitale Brovarone

Project Coordinator

Isella Vicini

Dissemination Manager

PROJECT DETAILS

PROJECT NUMBER: 101091852
PROJECT TITLE: Remodelling of the infarcted heart: piezoelectric multifunctional patch enabling the sequential release of therapeutic factors
TOPIC: HORIZON-CL4-2022-RESILIENCE-01-13
START DATE: 01 January 2023
DURATION: 48 Months
GRANTING AUTHORITY: European Health and Digital Executive Agency
EU CONTRIBUTION: € 4.050.412,50 Euro

“Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do notnecessarily reflect those of the European Union or the European Health and Digital Executive Agency (HADEA). Neither the European Union nor the granting authority can be held responsible for them.”

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